Treating Infertility With Clomid or Clomiphene

Wang Yan

Global Courant

After the diagnose of infertility has been established and the couple has been presented all possible treatments that can help in restoring fertility, they have to choose which method suits them best. Most of them choose, as their first option, undergoing a prescribed drugs treatment before taking into consideration, surgery or assisted fertilization methods like IVF (in vitro fertilization).

The fertilization drug with the highest success rate and used for over 30 years now is Clomid, a medication that induces ovulation by stimulating a woman’s ovaries into producing a higher number of follicles each month, thus maturing the eggs faster. And if the number of follicles is higher and the eggs are mature then is most likely to get pregnant easier.

On more medical terms, what Clomid actually does is stimulating and increasing the number of three hormones in the body that have important roles in the ovulation process by tricking the body into believing that the estrogen levels are low. These hormones are: GnRH – gonadotropine releasing hormone, LH – luteinizing hormone and FSH – follicle stimulating hormone.

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Unfortunately Clomid isn’t helpful in all cases of female infertility and it’s only prescribed if the infertility is caused by anovulation, irregular menstrual periods or PCOS. It is also recommended for women undergoing IVF, to help increase the success rate of the procedure.

As almost any drug is very easy to take, orally, on the days specified by the fertility doctor. Depending on the doctor there are multiple schemes of taking Clomid, to ensure its success but most likely you will have to take it either on days 3-7 of your cycle or 5-9. The starting dosage is of 50 mg per day and after the second month is increased until it reaches its maximum amount allowed of 200 mg per day. If after six months the fertility of the woman has not been restored then the treatment with Clomid is ceased letting the spot opened for other possible treatments.

As any other medication, Clomid has also its share of side effects and complications. Though most of the reported side effects are mild, once the dosage is increased women might end up with a more serious complication, known as the Ovarian Hyperstimulation Syndrome (OHSS) that even though in most cases disappears on its own it can leave behind a few problems like twisting of the ovaries, fluid in the stomach or liver and kidney issues.

The general side effects of Clomid can easily be mistaken with the first signs of a pregnancy and they are: mood swings, nausea, vomiting, headaches, fatigue and breast tenderness.

Clomid has a particularly high success rate especially in women suffering from ovulatory dysfunctions, and almost 90% of the women taking it have managed to ovulate within the first three or four months of the treatment. From this 90% almost half of them have managed to even get pregnant within the period of the treatment.

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Treating Infertility With Clomid or Clomiphene

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